Oral delivery is highly esteemed for its convenience and substantial consumer compliance, rendering it as a preferred method in contemporary healthcare. Nonetheless, the development of effective oral delivery systems is fraught with significant challenges, particularly in enhancing the solubility, permeability, and bioavailability of biomolecules and pharmaceutical agents. These challenges are inherently linked to the physicochemical properties of active molecules, which are critical determinants of their absorption efficiency within the gastrointestinal tract, thereby influencing therapeutic effectiveness and safety.

“S.A.A.M optimizes oral delivery by enhancing stability, solubility, and bioavailability for improved therapeutic efficacy.”

Self-Assembled Active Molecules (S.A.A.M) is a novel concept in oral delivery systems to make complex formulations which spontaneously organize themselves into well-defined structures, offering significant potential for drug delivery applications. Molecular self-assembly, by definition, is the spontaneous organization of molecules under thermodynamic equilibrium conditions (at particular pH and temperatures) into structurally well-defined and rather stable arrangements through a number of noncovalent interactions. S.A.A.M helps to increase the stability and bioavailability of molecules within biological systems—such as lowering stomach, gastrointestinal degradation and thereby improving permeability and absorption.